Robin Sequence: More Than a Receding Chin
By John Mulliken, MD, Director, Craniofacial Centre, Boston Children’s Hospital
Children born with Robin sequence (named for an early 20th century French physician; pronounced row-BAN) have a lower jaw that is smaller than normal (micrognathia) or set back from the upper jaw (retrognathia).
Congenital defects caused by a failure of neural crest cells to migrate into the first pharyngeal arch which can produce facial anomalies. Examples of first arch syndromes include Treacher Collins syndrome and Pierre Robin syndrome.